Search on: LIPOPROTEINS, HDL 
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Descriptor English:   Lipoproteins, HDL 
Descriptor Spanish:   Lipoproteínas HDL 
Descriptor Portuguese:   Lipoproteínas HDL 
Synonyms English:   Heavy Lipoproteins
alpha-1 Lipoprotein
HDL Lipoproteins
High Density Lipoproteins
Lipoproteins, Heavy
Lipoproteins, High-Density
alpha Lipoproteins
alpha-Lipoproteins
High-Density Lipoproteins  
Tree Number:   D10.532.432
D12.776.521.479
Definition English:   A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases. 
Indexing Annotation English:   hyperalphalipoproteinemia = LIPOPROTEINS, HDL /blood (IM) + HYPERLIPOPROTEINEMIAS (IM); hypoalphalipoproteinemia = LIPOPROTEINS, HDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); familial hypoalphalipoproteinemia = TANGIER DISEASE; /defic: consider also HYPOLIPOPROTEINEMIAS
See Related English:   Tangier Disease
 
History Note English:   74(72) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   8249 
Unique Identifier:   D008075 

Occurrence in VHL:
 

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